Standard

Myopia

RASGRF1 · rs3851677

Where this position leads

Condition: Myopia

rs3851677 Condition: Myopia Myopia Condition rs3851677 rs3851677 RASGRF1

What the study found

Who was studied 27,993 European ancestry cases, 36,275 European ancestry controls.

The effect Each copy of the T allele shifted the measure 0.0998 higher (95% confidence interval 0.077-0.122); p = 3 × 10−18.

Where it sits Chromosome 15, band 15q25.1 — in an intron of RASGRF1.

What each result means

C/C No copy of the version the research linked to Myopia. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Myopia. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Myopia. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs3851677

What is rs3851677?

rs3851677 is a single position in the genome, in or near the RASGRF1 gene. Published research associates it with myopia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs3851677 linked to?

On MyGeneLog this position is linked to Myopia. The research behind each link, and its sources, are set out on that condition page.

Does having rs3851677 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs3851677 come from?

GWAS Catalog, EBioMedicine 2022, PMID:35841873. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Myopia (rs3851677). MyGeneLog™. https://www.mygenelog.com/variants/rs3851677

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