0 323217223210Reads by AI crawlersClaude3ChatGPT2Google · Gemini0Perplexity1Meta AI7Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others10Total32Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 6,968 European ancestry cases, 20,464 European ancestry controls; replicated in 10,679 European ancestry cases, 26,715 European ancestry controls, 397 Iranian ancestry cases, 342 Iranian ancestry controls, 1,239 Indian ancestry cases, 990 Indian ancestry controls, 1,134 East Asian ancestry cases, 3,719 East Asian ancestry controls.
The effect
Each copy of the A allele carried 1.20 times the odds of Ulcerative colitis (95% confidence interval 1.16-1.25); p = 1 × 10−14.
How common The A allele had a frequency of about 6% in the people studied.
Where it sits Chromosome 6, band 6q21 — in an intron of TRAF3IP2-AS1.
What each result means
A/ATwo copies of the version the research linked to Ulcerative colitis. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/TOne copy of the version the research linked to Ulcerative colitis. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Ulcerative colitis. This is the starting point the study compared everyone against.
rs3851228 is a single position in the genome, in or near the near TRAF3IP2 gene. Published research associates it with ulcerative colitis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs3851228 linked to?
On MyGeneLog this position is linked to Ulcerative Colitis. The research behind each link, and its sources, are set out on that condition page.
Does having rs3851228 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs3851228 come from?
GWAS Catalog, Nat Genet 2015, PMID:26192919. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 323217223210Reads by AI crawlersClaude3ChatGPT2Google · Gemini0Perplexity1Meta AI7Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others10Total32Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.