A/APublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Ulcerative colitis compared to the general population. (GWAS Catalog, Nat Genet 2015, PMID:26192919)
A/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Ulcerative colitis. (GWAS Catalog, Nat Genet 2015, PMID:26192919)
T/TPublished research associates this genotype with typical/baseline likelihood of Ulcerative colitis — no copies of the reported risk allele. (GWAS Catalog, Nat Genet 2015, PMID:26192919)
rs3851228 is a single position in the genome, in or near the near TRAF3IP2 gene. Published research associates it with ulcerative colitis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs3851228 linked to?
On MyGeneLog this position is linked to Ulcerative Colitis. The research behind each link, and its sources, are set out on that condition page.
Does having rs3851228 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs3851228 come from?
GWAS Catalog, Nat Genet 2015, PMID:26192919. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.