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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 33,483 Japanese ancestry individuals.
The effect
Each copy of the C allele shifted the measure 0.05 lower (95% confidence interval 0.032-0.068); p = 4 × 10−10.
How common The C allele had a frequency of about 40% in the people studied.
Where it sits Chromosome 16, band 16p13.3 — in an intron of AXIN1.
What each result means
C/CTwo copies of the version the research linked to Axial length. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Axial length. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Axial length. This is the starting point the study compared everyone against.
Ophthalmology science · 2022 · PMID 36246171 · open access
Questions about rs3848363
What is rs3848363?
rs3848363 is a single position in the genome, in or near the AXIN1 gene. Published research associates it with axial length. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs3848363 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs3848363 come from?
GWAS Catalog, Ophthalmology science 2022, PMID:36246171. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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