Standard

Triglycerides

PRSS3 · rs3843935

Where this position leads

Condition: High Triglycerides

rs3843935 Condition: High Triglycerides High Triglycerides Condition rs3843935 rs3843935 PRSS3

What the study found

Who was studied 215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals; replicated in Up to 319,677 individuals.

The effect Each copy of the T allele shifted the measure 0.0155 mg dl-1 higher (95% confidence interval 0.011-0.02); p = 6 × 10−11.

How common The T allele had a frequency of about 39% in the people studied.

Where it sits Chromosome 9, band 9p13.3 — in an intron of UBE2R2-AS1.

What each result means

C/C No copy of the version the research linked to Triglycerides. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Triglycerides. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Triglycerides. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs3843935

What is rs3843935?

rs3843935 is a single position in the genome, in or near the PRSS3 gene. Published research associates it with triglycerides. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs3843935 linked to?

On MyGeneLog this position is linked to High Triglycerides. The research behind each link, and its sources, are set out on that condition page.

Does having rs3843935 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs3843935 come from?

GWAS Catalog, Nature genetics 2018, PMID:30275531. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Triglycerides (rs3843935). MyGeneLog™. https://www.mygenelog.com/variants/rs3843935

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