Gene Knowledge Graph
UTC
Standard

Systolic blood pressure

near PDP2 · rs3843712

Where this position leads

Condition: Blood Pressure

rs3843712 Condition: Blood Pressure Blood Pressure Condition rs3843712 rs3843712 near PDP2

What the study found

Who was studied 526,001 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.38 lower (95% confidence interval 0.26-0.5); p = 2 × 10−10.

Where it sits Chromosome 16, band 16q22.1 — between genes, 4.5 kb from PDP2.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Systolic blood pressure — no copies of the reported risk allele.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Systolic blood pressure.
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Systolic blood pressure compared to the general population.
Source
High Blood Pressure and Intraocular Pressure: A Mendelian Randomization Study
Plotnikov D, Huang Y, Khawaja AP, Foster PJ, Zhu Z, Guggenheim JA, He M
Investigative ophthalmology & visual science · 2022 · PMID 35762941 · open access

Questions about rs3843712

What is rs3843712?

rs3843712 is a single position in the genome, in or near the near PDP2 gene. Published research associates it with systolic blood pressure. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs3843712 linked to?

On MyGeneLog this position is linked to Blood Pressure. The research behind each link, and its sources, are set out on that condition page.

Does having rs3843712 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs3843712 come from?

GWAS Catalog, Investigative ophthalmology & visual science 2022, PMID:35762941. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Systolic blood pressure (rs3843712). MyGeneLog™. https://www.mygenelog.com/variants/rs3843712

← See all variants