Sensitive

Colorectal cancer

NOTCH4 · rs3830041

Where this position leads

Condition: Colorectal Cancer

rs3830041 Condition: Colorectal Cancer Colorectal Cancer Condition rs3830041 rs3830041 NOTCH4

What the study found

Who was studied 22,775 East Asian ancestry cases, 47,731 East Asian ancestry controls.

The effect Each copy of the T allele carried 1.16 times the odds of Colorectal cancer (95% confidence interval 1.10-1.21); p = 2 × 10−8.

How common The T allele had a frequency of about 14% in the people studied.

Where it sits Chromosome 6, band 6p21.32 — in an intron of NOTCH4.

What each result means

C/C No copy of the version the research linked to Colorectal cancer. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Colorectal cancer. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Colorectal cancer. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs3830041

What is rs3830041?

rs3830041 is a single position in the genome, in or near the NOTCH4 gene. Published research associates it with colorectal cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs3830041 linked to?

On MyGeneLog this position is linked to Colorectal Cancer. The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs3830041?

Subjects that appear in the title or abstract of the same papers as this rsID include infection and immunity (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs3830041 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs3830041 come from?

GWAS Catalog, Gastroenterology 2018, PMID:30529582. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Colorectal cancer (rs3830041). MyGeneLog™. https://www.mygenelog.com/variants/rs3830041

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