Standard

Hair thickness

EDAR · rs3827760

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What ClinVar records

Classification Benign for Hair morphology 1, hair thickness, Hypohidrotic ectodermal dysplasia, Non-syndromic oligodontia, Autosomal recessive hypohidrotic ectodermal dysplasia syndrome, Ectodermal dysplasia 10A, hypohidrotic/hair/nail type, autosomal dominant and 1 more; criteria provided, multiple submitters, no conflicts (2 of 4 stars, 10 submitters), last evaluated 2026-01-26. ClinVar record 5858 NM_022336.4(EDAR):c.1109T>C (p.Val370Ala)

What this is ClinVar's aggregate record for this position (as of its 2026-10-19 release), not a result about you. A classification describes the variant against the condition named, as laboratories submitted it. Whether a person carries this variant, and what that would mean for them, is a question for a clinical test and a genetic counsellor.

What each result means

A/A Typical EDAR activity in published research — associated with the ancestral hair-thickness profile.

A/G One copy of each allele. Published research associates this genotype with an intermediate effect on hair shaft thickness.

G/G Published research associates this genotype with thicker hair shafts, more scalp sweat glands, and a distinctive tooth-shape trait (shovel-shaped incisors) — one variant affecting several traits at once. Common in East Asian and Indigenous American populations, and one of the most well-documented examples of recent positive selection in the human genome.

Source

A scan for genetic determinants of human hair morphology: EDAR is associated with Asian hair thickness

Fujimoto A, Kimura R, Ohashi J, Omi K, Yuliwulandari R, Batubara L, Mustofa MS, Samakkarn U, Settheetham-Ishida W, Ishida T, Morishita Y, Furusawa T

and 3 more — show all

Nakazawa M, Ohtsuka R, Tokunaga K

Human molecular genetics · 2008 · PMID 18065779

What people read about alongside this

Natural selection5

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

From our blog

A strand of hair splitting apart to reveal a DNA double helix inside it

One Gene, Three Hair Types: Meet EDAR

A single DNA change near one gene, EDAR, tracks with three distinct hair-thickness profiles in published resea…

Questions about rs3827760

What is rs3827760?

rs3827760 is a single position in the genome, in or near the EDAR gene. Published research associates it with hair thickness. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What do people read about alongside rs3827760?

Subjects that appear in the title or abstract of the same papers as this rsID include natural selection (5 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs3827760 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs3827760 come from?

Fujimoto et al. 2008, Human Molecular Genetics — a scan for genetic determinants of human hair morphology identifies EDAR. PMID 18065779. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Hair thickness (rs3827760). MyGeneLog™. https://www.mygenelog.com/variants/rs3827760

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