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Coronary artery disease

PCIF1 · rs3827066

Where this position leads

Condition: Coronary Artery Disease

rs3827066 Condition: Coronary Artery Disease Coronary Artery Disease Condition rs3827066 rs3827066 PCIF1

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Coronary artery disease — no copies of the reported risk allele.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Coronary artery disease.
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Coronary artery disease compared to the general population.
Source
Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease
van der Harst P, Verweij N
Circulation research · 2018 · PMID 29212778 · open access

Questions about rs3827066

What is rs3827066?

rs3827066 is a single position in the genome, in or near the PCIF1 gene. Published research associates it with coronary artery disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs3827066 linked to?

On MyGeneLog this position is linked to Coronary Artery Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs3827066 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs3827066 come from?

GWAS Catalog, Circ Res 2017, PMID:29212778. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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