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Platelet count in first trimester

near SYT5 · rs3826887

What the study found

Who was studied 66,814 Chinese ancestry individuals; replicated in 36,616 Chinese ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0771 lower (95% confidence interval 0.055-0.1); p = 2 × 10−11.

How common The A allele had a frequency of about 21% in the people studied.

What each result means

A/A Two copies of the version the research linked to Platelet count in first trimester. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Platelet count in first trimester. That is a smaller link than two copies.
G/G No copy of the version the research linked to Platelet count in first trimester. This is the starting point the study compared everyone against.
Source

Questions about rs3826887

What is rs3826887?

rs3826887 is a single position in the genome, in or near the near SYT5 gene. Published research associates it with platelet count in first trimester. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs3826887 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs3826887 come from?

GWAS Catalog, Nature genetics 2026, PMID:42509370. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Platelet count in first trimester (rs3826887). MyGeneLog™. https://www.mygenelog.com/variants/rs3826887

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