Sensitive
Coronary heart disease
ADAMTS7 · rs3825807
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
A/A
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Coronary heart disease compared to the general population. (GWAS Catalog, Nat Genet 2011, PMID:21378990)
A/G
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Coronary heart disease. (GWAS Catalog, Nat Genet 2011, PMID:21378990)
G/G
Published research associates this genotype with typical/baseline likelihood of Coronary heart disease — no copies of the reported risk allele. (GWAS Catalog, Nat Genet 2011, PMID:21378990)
Source
Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease
Schunkert H,
König IR,
Kathiresan S,
Reilly MP,
Assimes TL,
Holm H,
Preuss M,
Stewart AF,
Barbalic M,
Gieger C,
Absher D,
Aherrahrou Z
and 155 more — show all
Allayee H,
Altshuler D,
Anand SS,
Andersen K,
Anderson JL,
Ardissino D,
Ball SG,
Balmforth AJ,
Barnes TA,
Becker DM,
Becker LC,
Berger K,
Bis JC,
Boekholdt SM,
Boerwinkle E,
Braund PS,
Brown MJ,
Burnett MS,
Buysschaert I,
Carlquist JF,
Chen L,
Cichon S,
Codd V,
Davies RW,
Dedoussis G,
Dehghan A,
Demissie S,
Devaney JM,
Diemert P,
Do R,
Doering A,
Eifert S,
Mokhtari NE,
Ellis SG,
Elosua R,
Engert JC,
Epstein SE,
de Faire U,
Fischer M,
Folsom AR,
Freyer J,
Gigante B,
Girelli D,
Gretarsdottir S,
Gudnason V,
Gulcher JR,
Halperin E,
Hammond N,
Hazen SL,
Hofman A,
Horne BD,
Illig T,
Iribarren C,
Jones GT,
Jukema JW,
Kaiser MA,
Kaplan LM,
Kastelein JJ,
Khaw KT,
Knowles JW,
Kolovou G,
Kong A,
Laaksonen R,
Lambrechts D,
Leander K,
Lettre G,
Li M,
Lieb W,
Loley C,
Lotery AJ,
Mannucci PM,
Maouche S,
Martinelli N,
McKeown PP,
Meisinger C,
Meitinger T,
Melander O,
Merlini PA,
Mooser V,
Morgan T,
Mühleisen TW,
Muhlestein JB,
Münzel T,
Musunuru K,
Nahrstaedt J,
Nelson CP,
Nöthen MM,
Olivieri O,
Patel RS,
Patterson CC,
Peters A,
Peyvandi F,
Qu L,
Quyyumi AA,
Rader DJ,
Rallidis LS,
Rice C,
Rosendaal FR,
Rubin D,
Salomaa V,
Sampietro ML,
Sandhu MS,
Schadt E,
Schäfer A,
Schillert A,
Schreiber S,
Schrezenmeir J,
Schwartz SM,
Siscovick DS,
Sivananthan M,
Sivapalaratnam S,
Smith A,
Smith TB,
Snoep JD,
Soranzo N,
Spertus JA,
Stark K,
Stirrups K,
Stoll M,
Tang WH,
Tennstedt S,
Thorgeirsson G,
Thorleifsson G,
Tomaszewski M,
Uitterlinden AG,
van Rij AM,
Voight BF,
Wareham NJ,
Wells GA,
Wichmann HE,
Wild PS,
Willenborg C,
Witteman JC,
Wright BJ,
Ye S,
Zeller T,
Ziegler A,
Cambien F,
Goodall AH,
Cupples LA,
Quertermous T,
März W,
Hengstenberg C,
Blankenberg S,
Ouwehand WH,
Hall AS,
Deloukas P,
Thompson JR,
Stefansson K,
Roberts R,
Thorsteinsdottir U,
O'Donnell CJ,
McPherson R,
Erdmann J,
Samani NJ
Nature genetics · 2011 · PMID 21378990
Questions about rs3825807
What is rs3825807?
rs3825807 is a single position in the genome, in or near the ADAMTS7 gene. Published research associates it with coronary heart disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs3825807 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs3825807 come from?
GWAS Catalog, Nat Genet 2011, PMID:21378990. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants