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Platelet count

STON2 · rs3825606

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What the study found

Who was studied 153,950 Korean ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0349 higher (95% confidence interval 0.028-0.042); p = 3 × 10⁻²⁰.

How common The A allele had a frequency of about 43% in the people studied.

Where it sits Chromosome 14, band 14q31.1 — in an intron of STON2.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Platelet count compared to the general population.

A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Platelet count.

G/G Published research associates this genotype with typical/baseline likelihood of Platelet count — no copies of the reported risk allele.

Source

Genome-wide association studies in a large Korean cohort identify quantitative trait loci for 36 traits and illuminate their genetic architectures

Jee YH, Wang Y, Jung KJ, Lee JY, Kimm H, Duan R, Price AL, Martin AR, Kraft P

Nature communications · 2025 · PMID 40436827 · open access

Questions about rs3825606

What is rs3825606?

rs3825606 is a single position in the genome, in or near the STON2 gene. Published research associates it with platelet count. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs3825606 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs3825606 come from?

GWAS Catalog, Nature communications 2025, PMID:40436827. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Platelet count (rs3825606). MyGeneLog™. https://www.mygenelog.com/variants/rs3825606

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