3 401226122222Reads by AI crawlersClaude1ChatGPT2Google · Gemini0Perplexity2Meta AI6Microsoft · Copilot1Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others22Total40Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 2,296 European ancestry cases, 5,171 European ancestry controls; replicated in 2,753 European ancestry cases, 4,569 European ancestry controls.
The effect
Each copy of the A allele carried 1.30 times the odds of Systemic sclerosis (95% confidence interval 1.19-1.41); p = 3 × 10−9.
How common The A allele had a frequency of about 20% in the people studied.
Where it sits Chromosome 2, band 2q32.2 — in an intron of STAT4.
What each result means
A/ATwo copies of the version the research linked to Systemic sclerosis. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Systemic sclerosis. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Systemic sclerosis. This is the starting point the study compared everyone against.
Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.
Questions about rs3821236
What is rs3821236?
rs3821236 is a single position in the genome, in or near the STAT4 gene. Published research associates it with systemic sclerosis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs3821236 linked to?
On MyGeneLog this position is linked to Systemic Sclerosis. The research behind each link, and its sources, are set out on that condition page.
What do people read about alongside rs3821236?
Subjects that appear in the title or abstract of the same papers as this rsID include blood sugar and insulin (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.
Does having rs3821236 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs3821236 come from?
GWAS Catalog, Nat Genet 2010, PMID:20383147. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
3 401226122222Reads by AI crawlersClaude1ChatGPT2Google · Gemini0Perplexity2Meta AI6Microsoft · Copilot1Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others22Total40Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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