Standard

Pulmonary function

GPR126 · rs3817928

Where this position leads

Condition: Pulmonary Function (Lung Capacity)

rs3817928 Condition: Pulmonary Function (Lung Capacity) Pulmonary Function (Lung Capacity) Condition rs3817928 rs3817928 GPR126

What the study found

Who was studied 20,890 European ancestry individuals; replicated in 16,178 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.42 % lower; p = 1 × 10−9.

How common The A allele had a frequency of about 78% in the people studied.

Where it sits Chromosome 6, band 6q24.2 — in an intron of ADGRG6.

What each result means

A/A Two copies of the version the research linked to Pulmonary function. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Pulmonary function. That is a smaller link than two copies.
G/G No copy of the version the research linked to Pulmonary function. This is the starting point the study compared everyone against.
Source

Questions about rs3817928

What is rs3817928?

rs3817928 is a single position in the genome, in or near the GPR126 gene. Published research associates it with pulmonary function. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs3817928 linked to?

On MyGeneLog this position is linked to Pulmonary Function (Lung Capacity). The research behind each link, and its sources, are set out on that condition page.

Does having rs3817928 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs3817928 come from?

GWAS Catalog, Nature genetics 2010, PMID:20010835. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Pulmonary function (rs3817928). MyGeneLog™. https://www.mygenelog.com/variants/rs3817928

← See all variants