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Glutathione S-transferase Mu 4 levels

GSTM2 · rs3815026

What the study found

Who was studied 10,708 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.579 higher (95% confidence interval 0.55-0.61); p = 4 × 10−305.

How common The C allele had a frequency of about 50% in the people studied.

Where it sits Chromosome 1, band 1p13.3 — in the 5′ untranslated region of GSTM2.

What each result means

C/C Two copies of the version the research linked to Glutathione S-transferase Mu 4 levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/G One copy of the version the research linked to Glutathione S-transferase Mu 4 levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to Glutathione S-transferase Mu 4 levels. This is the starting point the study compared everyone against.
Source

Questions about rs3815026

What is rs3815026?

rs3815026 is a single position in the genome, in or near the GSTM2 gene. Published research associates it with glutathione s-transferase mu 4 levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs3815026 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs3815026 come from?

GWAS Catalog, Science (New York, N.Y.) 2021, PMID:34648354. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Glutathione S-transferase Mu 4 levels (rs3815026). MyGeneLog™. https://www.mygenelog.com/variants/rs3815026

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