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C-reactive protein levels

USP44 · rs3812814

Where this position leads

Condition: C-Reactive Protein Levels

rs3812814 Condition: C-Reactive Protein Levels C-Reactive Protein Levels Condition rs3812814 rs3812814 USP44

What the study found

Who was studied 341,805 European ancestry individuals, 6,006 African ancestry individuals, 7,316 South Asian ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0247 higher (95% confidence interval 0.017-0.032); p = 1 × 10−11.

Where it sits Chromosome 12, band 12q22 — a synonymous change in USP44.

What each result means

A/A No copy of the version the research linked to C-reactive protein levels. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to C-reactive protein levels. That is a smaller link than two copies.
G/G Two copies of the version the research linked to C-reactive protein levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs3812814

What is rs3812814?

rs3812814 is a single position in the genome, in or near the USP44 gene. Published research associates it with c-reactive protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs3812814 linked to?

On MyGeneLog this position is linked to C-Reactive Protein Levels. The research behind each link, and its sources, are set out on that condition page.

Does having rs3812814 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs3812814 come from?

GWAS Catalog, Nature genetics 2021, PMID:33462484. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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C-reactive protein levels (rs3812814). MyGeneLog™. https://www.mygenelog.com/variants/rs3812814

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