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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 1,383 Danish ancestry cases, 62,656 Danish ancestry controls.
The effect
Each copy of the T allele carried 1.31 times the odds of Autoimmune traits (95% confidence interval 1.21-1.42); p = 1 × 10−10.
How common The T allele had a frequency of about 29% in the people studied.
Where it sits Chromosome 6, band 6p21.32 — between genes, 0 kb from HLA-DOA.
What each result means
G/GNo copy of the version the research linked to Autoimmune traits. This is the starting point the study compared everyone against.
G/TOne copy of the version the research linked to Autoimmune traits. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Autoimmune traits. That is the strongest link of the three results. A link in a study is not a diagnosis.
Brain, behavior, and immunity · 2021 · PMID 32534018
Questions about rs381218
What is rs381218?
rs381218 is a single position in the genome, in or near the near HLA-DOA gene. Published research associates it with autoimmune traits. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs381218 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs381218 come from?
GWAS Catalog, Brain, behavior, and immunity 2021, PMID:32534018. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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