Sensitive

Metabolic dysfunction-associated steatotic liver disease (MTAG)

DOCK6 · rs3810308

What the study found

Who was studied 122,644 European ancestry individuals (MTAG effective sample size boosted by proton density fat fraction samples).

The effect Each copy of the T allele shifted the measure 0.0432 lower (95% confidence interval 0.03-0.057); p = 2 × 10−10.

How common The T allele had a frequency of about 91% in the people studied.

Where it sits Chromosome 19, band 19p13.2 — inside DOCK6.

What each result means

C/C No copy of the version the research linked to Metabolic dysfunction-associated steatotic liver disease (MTAG). This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Metabolic dysfunction-associated steatotic liver disease (MTAG). That is a smaller link than two copies.
T/T Two copies of the version the research linked to Metabolic dysfunction-associated steatotic liver disease (MTAG). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs3810308

What is rs3810308?

rs3810308 is a single position in the genome, in or near the DOCK6 gene. Published research associates it with metabolic dysfunction-associated steatotic liver disease (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs3810308 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs3810308 come from?

GWAS Catalog, Science advances 2026, PMID:41686896. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Metabolic dysfunction-associated steatotic liver disease (MTAG) (rs3810308). MyGeneLog™. https://www.mygenelog.com/variants/rs3810308

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