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Eye color

MAP2K6 · rs3809761

Where this position leads

Condition: Eye Color and Pigmentation

rs3809761 Condition: Eye Color and Pigmentation Eye Color and Pigmentation Condition rs3809761 rs3809761 MAP2K6

What the study found

Who was studied 157,485 European ancestry individuals; replicated in 35,501 European ancestry individuals, 959 Han Chinese ancestry individuals, 677 Indian ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.059 higher (95% confidence interval 0.039-0.079); p = 5 × 10−9.

How common The G allele had a frequency of about 81% in the people studied.

Where it sits Chromosome 17, band 17q24.3 — in an intron of MAP2K6.

What each result means

A/A No copy of the version the research linked to Eye color. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Eye color. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Eye color. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs3809761

What is rs3809761?

rs3809761 is a single position in the genome, in or near the MAP2K6 gene. Published research associates it with eye color. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs3809761 linked to?

On MyGeneLog this position is linked to Eye Color and Pigmentation. The research behind each link, and its sources, are set out on that condition page.

Does having rs3809761 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs3809761 come from?

GWAS Catalog, Science advances 2021, PMID:33692100. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Eye color (rs3809761). MyGeneLog™. https://www.mygenelog.com/variants/rs3809761

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