Standard

PR interval

CAV1 · rs3807989

Where this position leads

Condition: Cardiac Conduction Intervals (PR Interval and QRS Duration)

rs3807989 Condition: Cardiac Conduction Intervals (PR Interval and QRS Duration) Cardiac Conduction Intervals (PR In… Condition Topic: Heart and circulation Heart and circulation Topic rs3807989 rs3807989 CAV1

Solid lines are connections this site curates. Dashed lines mean the two ends share a research paper — worth knowing, and not a claim that one explains the other.

What the study found

Who was studied 28,517 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 2.3 ms higher (95% confidence interval 1.89-2.71); p = 4 × 10−28.

How common The A allele had a frequency of about 40% in the people studied.

Where it sits Chromosome 7, band 7q31.2 — in an intron of CAV1.

What each result means

A/A Two copies of the version the research linked to PR interval. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to PR interval. That is a smaller link than two copies.
G/G No copy of the version the research linked to PR interval. This is the starting point the study compared everyone against.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs3807989

What is rs3807989?

rs3807989 is a single position in the genome, in or near the CAV1 gene. Published research associates it with pr interval. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs3807989 linked to?

On MyGeneLog this position is linked to Cardiac Conduction Intervals (PR Interval and QRS Duration). The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs3807989?

Subjects that appear in the title or abstract of the same papers as this rsID include heart and circulation (12 papers), blood sugar and insulin (2 papers), cholesterol and blood fats (1 papers), infection and immunity (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs3807989 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs3807989 come from?

GWAS Catalog, Nat Genet 2010, PMID:20062060. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

PR interval (rs3807989). MyGeneLog™. https://www.mygenelog.com/variants/rs3807989

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