Venous thromboembolism adjusted for sickle cell variant rs77121243-T
LY86 · rs3804476
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Who was studied 393 African American cases, 4,941 African American controls..
The effect
Each copy of the G allele carried 1.83 times the odds of Venous thromboembolism adjusted for sickle cell variant rs77121243-T (95% confidence interval 1.481-2.256); p = 2 × 10−8.
How common The G allele had a frequency of about 13% in the people studied.
Where it sits Chromosome 6, band 6p25.1 — in an intron of LY86.
What each result means
A/ANo copy of the version the research linked to Venous thromboembolism adjusted for sickle cell variant rs77121243-T. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Venous thromboembolism adjusted for sickle cell variant rs77121243-T. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Venous thromboembolism adjusted for sickle cell variant rs77121243-T. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs3804476 is a single position in the genome, in or near the LY86 gene. Published research associates it with venous thromboembolism adjusted for sickle cell variant rs77121243-t. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs3804476 linked to?
On MyGeneLog this position is linked to Venous Thromboembolism. The research behind each link, and its sources, are set out on that condition page.
Does having rs3804476 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs3804476 come from?
GWAS Catalog, Thromb Haemost 2017, PMID:28203683. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
2 34115223119Reads by AI crawlersClaude0ChatGPT0Google · Gemini1Perplexity1Meta AI5Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others19Total34Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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