Sensitive

Polycystic ovary syndrome

C9orf3 · rs3802457

Where this position leads

Condition: Polycystic Ovary Syndrome

rs3802457 Condition: Polycystic Ovary Syndrome Polycystic Ovary Syndrome Condition rs3802457 rs3802457 C9orf3

What the study found

Who was studied 2,254 Han Chinese ancestry cases, 3,001 Han Chinese ancestry controls; replicated in 8,226 Han Chinese ancestry cases, 7,578 Han Chinese ancestry controls.

The effect Each copy of the G allele carried 1.30 times the odds of Polycystic ovary syndrome; p = 5 × 10−14.

How common The G allele had a frequency of about 90% in the people studied.

Where it sits Chromosome 9, band 9q22.32 — in an intron of AOPEP.

What each result means

A/A No copy of the version the research linked to Polycystic ovary syndrome. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Polycystic ovary syndrome. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Polycystic ovary syndrome. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs3802457

What is rs3802457?

rs3802457 is a single position in the genome, in or near the C9orf3 gene. Published research associates it with polycystic ovary syndrome. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs3802457 linked to?

On MyGeneLog this position is linked to Polycystic Ovary Syndrome. The research behind each link, and its sources, are set out on that condition page.

Does having rs3802457 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs3802457 come from?

GWAS Catalog, Nat Genet 2012, PMID:22885925. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Polycystic ovary syndrome (rs3802457). MyGeneLog™. https://www.mygenelog.com/variants/rs3802457

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