Sensitive

Post-traumatic stress disorder symptom severity (total)

MAD1L1 · rs3800872

What the study found

Who was studied 186,689 European ancestry individuals, up to 51,036 African ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.374 higher; p = 4 × 10−11.

Where it sits Chromosome 7, band 7p22.3 — in an intron of MAD1L1.

What each result means

C/C Two copies of the version the research linked to Post-traumatic stress disorder symptom severity (total). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/G One copy of the version the research linked to Post-traumatic stress disorder symptom severity (total). That is a smaller link than two copies.
G/G No copy of the version the research linked to Post-traumatic stress disorder symptom severity (total). This is the starting point the study compared everyone against.
Source

Questions about rs3800872

What is rs3800872?

rs3800872 is a single position in the genome, in or near the MAD1L1 gene. Published research associates it with post-traumatic stress disorder symptom severity (total). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs3800872 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs3800872 come from?

GWAS Catalog, Nature genetics 2021, PMID:33510476. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Post-traumatic stress disorder symptom severity (total) (rs3800872). MyGeneLog™. https://www.mygenelog.com/variants/rs3800872

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