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Right hippocampal volume (body)

FOXO3 · rs3800232

What the study found

Who was studied 38,977 European ancestry, East Asian ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.067 lower (95% confidence interval 0.047-0.087); p = 5 × 10−11.

How common The T allele had a frequency of about 17% in the people studied.

Where it sits Chromosome 6, band 6q21 — in an intron of FOXO3.

What each result means

C/C No copy of the version the research linked to Right hippocampal volume (body). This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Right hippocampal volume (body). That is a smaller link than two copies.
T/T Two copies of the version the research linked to Right hippocampal volume (body). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs3800232

What is rs3800232?

rs3800232 is a single position in the genome, in or near the FOXO3 gene. Published research associates it with right hippocampal volume (body). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs3800232 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs3800232 come from?

GWAS Catalog, Nature genetics 2023, PMID:37337106. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Right hippocampal volume (body) (rs3800232). MyGeneLog™. https://www.mygenelog.com/variants/rs3800232

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