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Alanine aminotransferase levels

FRK · rs3798232

What the study found

Who was studied 507,850 East Asian ancestry individuals, 420,829 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0151 lower (95% confidence interval 0.012-0.018); p = 2 × 10−21.

Where it sits Chromosome 6, band 6q22.1 — in an intron of FRK.

What each result means

C/C No copy of the version the research linked to Alanine aminotransferase levels. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Alanine aminotransferase levels. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Alanine aminotransferase levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs3798232

What is rs3798232?

rs3798232 is a single position in the genome, in or near the FRK gene. Published research associates it with alanine aminotransferase levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs3798232 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs3798232 come from?

GWAS Catalog, Nature communications 2025, PMID:40436827. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Alanine aminotransferase levels (rs3798232). MyGeneLog™. https://www.mygenelog.com/variants/rs3798232

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