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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 2,101 European ancestry child cases, 4,202 European ancestry controls; replicated in 365 African American child cases, 2,491 African American controls, 427 European ancestry cases, 783 European ancestry controls, 371 cases, 1,122 controls.
The effect
Each copy of the A allele carried 1.30 times the odds of Sporadic neuroblastoma (95% confidence interval 1.21-1.40); p = 1 × 10−12.
How common The A allele had a frequency of about 30% in the people studied.
Where it sits Chromosome 4, band 4p16.1 — in an intron of GPR78.
What each result means
A/ATwo copies of the version the research linked to Sporadic neuroblastoma. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Sporadic neuroblastoma. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Sporadic neuroblastoma. This is the starting point the study compared everyone against.
PLoS genetics · 2017 · PMID 28545128 · open access
Questions about rs3796727
What is rs3796727?
rs3796727 is a single position in the genome, in or near the CPZ gene. Published research associates it with sporadic neuroblastoma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs3796727 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs3796727 come from?
GWAS Catalog, PLoS genetics 2017, PMID:28545128. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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