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Systolic blood pressure

GUCY1A1 · rs3796582

Where this position leads

Condition: Blood Pressure

rs3796582 Condition: Blood Pressure Blood Pressure Condition rs3796582 rs3796582 GUCY1A1

What the study found

Who was studied 526,001 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.317 higher (95% confidence interval 0.24-0.39); p = 2 × 10−17.

Where it sits Chromosome 4, band 4q32.1 — in an intron of GUCY1A1.

What each result means

C/C No copy of the version the research linked to Systolic blood pressure. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Systolic blood pressure. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Systolic blood pressure. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs3796582

What is rs3796582?

rs3796582 is a single position in the genome, in or near the GUCY1A1 gene. Published research associates it with systolic blood pressure. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs3796582 linked to?

On MyGeneLog this position is linked to Blood Pressure. The research behind each link, and its sources, are set out on that condition page.

Does having rs3796582 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs3796582 come from?

GWAS Catalog, Investigative ophthalmology & visual science 2022, PMID:35762941. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Systolic blood pressure (rs3796582). MyGeneLog™. https://www.mygenelog.com/variants/rs3796582

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