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Migraine

MEF2D · rs3790455

Where this position leads

Condition: Migraine

rs3790455 Condition: Migraine Migraine Condition rs3790455 rs3790455 MEF2D

What the study found

Who was studied 2,326 European ancestry cases, 4,580 European ancestry controls; replicated in 2,508 European ancestry cases, 2,652 European ancestry controls.

The effect Each copy of the C allele carried 1.20 times the odds of Migraine (95% confidence interval 1.14-1.27); p = 7 × 10−11.

How common The C allele had a frequency of about 34% in the people studied.

Where it sits Chromosome 1, band 1q22 — in the 5′ untranslated region of MEF2D.

What each result means

C/C Two copies of the version the research linked to Migraine. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Migraine. That is a smaller link than two copies.
T/T No copy of the version the research linked to Migraine. This is the starting point the study compared everyone against.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs3790455

What is rs3790455?

rs3790455 is a single position in the genome, in or near the MEF2D gene. Published research associates it with migraine. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs3790455 linked to?

On MyGeneLog this position is linked to Migraine. The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs3790455?

Subjects that appear in the title or abstract of the same papers as this rsID include brain and memory (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs3790455 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs3790455 come from?

GWAS Catalog, Nat Genet 2012, PMID:22683712. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Migraine (rs3790455). MyGeneLog™. https://www.mygenelog.com/variants/rs3790455

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