CTBP2 · rs3781411
Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 98,060 European ancestry active cases, 162,995 European ancestry inactive controls.
The effect The reported allele is C; the catalogue records no effect size ; p = 3 × 10−10.
How common The C allele had a frequency of about 88% in the people studied.
Where it sits Chromosome 10, band 10q26.13 — a missense change in CTBP2.
rs3781411 is a single position in the genome, in or near the CTBP2 gene. Published research associates it with vigorous physical activity. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, International journal of obesity (2005) 2018, PMID:29899525. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Vigorous physical activity (rs3781411). MyGeneLog™. https://www.mygenelog.com/variants/rs3781411