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Body shape phenotype PC2

ICA1 · rs3779368

What the study found

Who was studied 460,198 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0161 lower (95% confidence interval 0.011-0.021); p = 2 × 10−10.

How common The C allele had a frequency of about 74% in the people studied.

Where it sits Chromosome 7, band 7p21.3 — in an intron of ICA1.

What each result means

C/C Two copies of the version the research linked to Body shape phenotype PC2. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Body shape phenotype PC2. That is a smaller link than two copies.
T/T No copy of the version the research linked to Body shape phenotype PC2. This is the starting point the study compared everyone against.
Source

Questions about rs3779368

What is rs3779368?

rs3779368 is a single position in the genome, in or near the ICA1 gene. Published research associates it with body shape phenotype pc2. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs3779368 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs3779368 come from?

GWAS Catalog, Science advances 2024, PMID:38640244. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Body shape phenotype PC2 (rs3779368). MyGeneLog™. https://www.mygenelog.com/variants/rs3779368

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