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Paraspinal proton density fat fraction

EYA4 · rs3777866

What the study found

Who was studied 37,589 British ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.06 higher (95% confidence interval 0.04-0.08); p = 1 × 10−11.

How common The T allele had a frequency of about 32% in the people studied.

Where it sits Chromosome 6, band 6q23.2 — in an intron of EYA4.

What each result means

C/C No copy of the version the research linked to Paraspinal proton density fat fraction. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Paraspinal proton density fat fraction. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Paraspinal proton density fat fraction. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs3777866

What is rs3777866?

rs3777866 is a single position in the genome, in or near the EYA4 gene. Published research associates it with paraspinal proton density fat fraction. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs3777866 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs3777866 come from?

GWAS Catalog, Journal of obesity 2025, PMID:40922984. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Paraspinal proton density fat fraction (rs3777866). MyGeneLog™. https://www.mygenelog.com/variants/rs3777866

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