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Who was studied up to 122,733 cases, up to 424,528 controls.
The effect
Each copy of the A allele shifted the measure 0.0386 higher (95% confidence interval 0.025-0.052); p = 8 × 10−9.
How common The A allele had a frequency of about 23% in the people studied.
Where it sits Chromosome 4, band 4q22.3 — in an intron of UNC5C.
What each result means
A/ATwo copies of the version the research linked to Coronary artery disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/TOne copy of the version the research linked to Coronary artery disease. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Coronary artery disease. This is the starting point the study compared everyone against.
Circulation research · 2018 · PMID 29212778 · open access
Questions about rs3775058
What is rs3775058?
rs3775058 is a single position in the genome, in or near the UNC5C gene. Published research associates it with coronary artery disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs3775058 linked to?
On MyGeneLog this position is linked to Coronary Artery Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs3775058 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs3775058 come from?
GWAS Catalog, Circulation research 2018, PMID:29212778. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 110Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others0Total1Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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