Alzheimer's disease or gastroesophageal reflux disease
SEMA3F · rs3774745
0 162113Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others13Total16Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 71,880 European ancestry Alzheimer's disease or AD-by-proxy cases, 71,522 European ancestry GERD cases, up to 644,457 European ancestry controls.
The effect
The reported allele is T; the catalogue records no effect size
; p = 2 × 10−9.
Where it sits Chromosome 3, band 3p21.31 — in an intron of SEMA3F.
What each result means
C/CNo copy of the version the research linked to Alzheimer's disease or gastroesophageal reflux disease. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Alzheimer's disease or gastroesophageal reflux disease. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Alzheimer's disease or gastroesophageal reflux disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
Communications biology · 2022 · PMID 35851147 · open access
Questions about rs3774745
What is rs3774745?
rs3774745 is a single position in the genome, in or near the SEMA3F gene. Published research associates it with alzheimer's disease or gastroesophageal reflux disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs3774745 linked to?
On MyGeneLog this position is linked to Alzheimer's Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs3774745 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs3774745 come from?
GWAS Catalog, Communications biology 2022, PMID:35851147. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 162113Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others13Total16Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Alzheimer's disease or gastroesophageal reflux disease (rs3774745). MyGeneLog™. https://www.mygenelog.com/variants/rs3774745