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Who was studied 38,000 South Asian ancestry individuals.
The effect
Each copy of the C allele shifted the measure 0.604 lower (95% confidence interval 0.54-0.67); p = 5 × 10−71.
Where it sits Chromosome 16, band 16p13.3 — in an intron of RAB11FIP3.
What each result means
C/CTwo copies of the version the research linked to Mean corpuscular hemoglobin. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/GOne copy of the version the research linked to Mean corpuscular hemoglobin. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Mean corpuscular hemoglobin. This is the starting point the study compared everyone against.
Nature communications · 2024 · PMID 39414775 · open access
Questions about rs377134808
What is rs377134808?
rs377134808 is a single position in the genome, in or near the RAB11FIP3 gene. Published research associates it with mean corpuscular hemoglobin. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs377134808 linked to?
On MyGeneLog this position is linked to Blood Cell Counts. The research behind each link, and its sources, are set out on that condition page.
Does having rs377134808 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs377134808 come from?
GWAS Catalog, Nature communications 2024, PMID:39414775. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
1 1823112Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others12Total18Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Mean corpuscular hemoglobin (rs377134808). MyGeneLog™. https://www.mygenelog.com/variants/rs377134808