0 1312217Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple2China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others7Total13Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 252,438 European ancestry cases, 1,959,739 European ancestry controls, 9,826 East Asian ancestry cases, 140,446 East Asian ancestry controls, 754 South Asian ancestry cases, 52,054 South Asian ancestry controls, 9,485 African ancestry cases, 109,006 African ancestry controls, 3,447 Admixed American ancestry cases, 46,818 Admixed American ancestry controls.
The effect
Each copy of the T allele shifted the measure 0.0347 higher (95% confidence interval 0.028-0.041); p = 3 × 10−25.
How common The T allele had a frequency of about 60% in the people studied.
Where it sits Chromosome 2, band 2p15 — in an intron of XPO1.
What each result means
G/GNo copy of the version the research linked to Atrial fibrillation. This is the starting point the study compared everyone against.
G/TOne copy of the version the research linked to Atrial fibrillation. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Atrial fibrillation. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2025 · PMID 40645996 · open access
Questions about rs3771260
What is rs3771260?
rs3771260 is a single position in the genome, in or near the XPO1 gene. Published research associates it with atrial fibrillation. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs3771260 linked to?
On MyGeneLog this position is linked to Atrial Fibrillation. The research behind each link, and its sources, are set out on that condition page.
Does having rs3771260 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs3771260 come from?
GWAS Catalog, Nature communications 2025, PMID:40645996. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 1312217Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple2China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others7Total13Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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