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Interleukin-1 receptor-like 1 levels

IL18R1 · rs3771167

What the study found

Who was studied 997 European ancestry individuals; replicated in 338 Greater Middle Eastern (Middle Eastern, North African or Persian), South Asian ancestry, Asian ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.436 higher (95% confidence interval 0.31-0.56); p = 1 × 10−11.

Where it sits Chromosome 2, band 2q12.1 — in an intron of IL18R1.

What each result means

A/A No copy of the version the research linked to Interleukin-1 receptor-like 1 levels. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Interleukin-1 receptor-like 1 levels. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Interleukin-1 receptor-like 1 levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs3771167

What is rs3771167?

rs3771167 is a single position in the genome, in or near the IL18R1 gene. Published research associates it with interleukin-1 receptor-like 1 levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs3771167 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs3771167 come from?

GWAS Catalog, Nature communications 2017, PMID:28240269. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Interleukin-1 receptor-like 1 levels (rs3771167). MyGeneLog™. https://www.mygenelog.com/variants/rs3771167

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