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Body mass index

CRIM1 · rs3770890

Where this position leads

Conditions: Childhood Body Mass Index, Obesity and Body Weight

rs3770890 Condition: Childhood Body Mass Index Childhood Body Mass Index Condition Condition: Obesity and Body Weight Obesity and Body Weight Condition rs3770890 rs3770890 CRIM1

What the study found

Who was studied 441,761 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0341 lower (95% confidence interval 0.022-0.046); p = 8 × 10−9.

Where it sits Chromosome 2, band 2p22.2 — in an intron of CRIM1.

What each result means

G/G No copy of the version the research linked to Body mass index. This is the starting point the study compared everyone against.
G/T One copy of the version the research linked to Body mass index. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Body mass index. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs3770890

What is rs3770890?

rs3770890 is a single position in the genome, in or near the CRIM1 gene. Published research associates it with body mass index. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs3770890 linked to?

On MyGeneLog this position is linked to Childhood Body Mass Index, Obesity and Body Weight. The research behind each link, and its sources, are set out on that condition page.

Does having rs3770890 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs3770890 come from?

GWAS Catalog, Diabetologia 2023, PMID:37280435. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Body mass index (rs3770890). MyGeneLog™. https://www.mygenelog.com/variants/rs3770890

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