Left eye overall retinal pigment epithelium thickness
PECR · rs3770526
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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 29,550 European ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.11 higher; p = 3 × 10−16.
Where it sits Chromosome 2, band 2q35 — in an intron of MREG.
What each result means
C/CNo copy of the version the research linked to Left eye overall retinal pigment epithelium thickness. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Left eye overall retinal pigment epithelium thickness. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Left eye overall retinal pigment epithelium thickness. That is the strongest link of the three results. A link in a study is not a diagnosis.
Pigment cell & melanoma research · 2025 · PMID 40650424 · open access
Questions about rs3770526
What is rs3770526?
rs3770526 is a single position in the genome, in or near the PECR gene. Published research associates it with left eye overall retinal pigment epithelium thickness. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs3770526 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs3770526 come from?
GWAS Catalog, Pigment cell & melanoma research 2025, PMID:40650424. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Left eye overall retinal pigment epithelium thickness (rs3770526). MyGeneLog™. https://www.mygenelog.com/variants/rs3770526