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Standard
Height
LTBP1 · rs3769528
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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
Strength of the evidence
3 / 4
Its strongest genetic-study result is p = 10−67, with 5 associations in the GWAS Catalog.
How this is scored
4: ClinVar disease-causing, reviewed by an expert panel or a guideline (3–4 stars). 3: ClinVar, several labs agreeing (2 stars), or a genetic study at p ≤ 10−50. 2: ClinVar from one lab (1 star), or p ≤ 10−20. 1: ClinVar submitted without criteria (0 stars), or genome-wide significance (p ≤ 5×10−8). The higher of the two counts. It says how solid the evidence is, not whether it matters for a particular person.
What the study found
Who was studied 472,730 East Asian ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.0559 lower (95% confidence interval 0.05-0.062); p = 2 × 10−67.
How common The G allele had a frequency of about 17% in the people studied.
Where it sits Chromosome 2, band 2p22.3 — in an intron of LTBP1.
How common each version is
AG
KoreanKRGDB
A 81.5% · G 18.5%
KoreanKorea4K
A 83.0% · G 17.0%
Japanese ToMMo
A 85.1% · G 14.9%
Vietnamese
A 87.5% · G 12.5%
World gnomAD
A 98.6% · G 1.4%
World 1000 Genomes
A 94.2% · G 5.8%
World TOPMed
A 98.5% · G 1.5%
By ancestry gnomAD
East Asian
A 83.3% · G 16.7%
European (non-Finnish)
A 99.9%
African / African American
A 99.1% · G 0.9%
South Asian
A 90.3% · G 9.7%
Admixed American (Latino)
A 98.5% · G 1.5%
Middle Eastern
A 98.6% · G 1.4%
Finnish
A 99.9%
Ashkenazi Jewish
A 99.9%
The share of all copies of this position that are each version. Source: the population studies published in dbSNP (US NCBI); each row names its study. The ancestry rows are gnomAD's own groups (via Ensembl), as the survey defines them, not races.
What each result means
A/ANo copy of the version the research linked to Height. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Height. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Height. That is the strongest link of the three results. A link in a study is not a diagnosis.
2 15122217Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot2Amazon2Apple2China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others7Total15Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
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