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Laminin subunit gamma-2 levels (LAMC2.9580.5.3)

LAMC2 · rs3768610

What the study found

Who was studied 3,301 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.47 lower (95% confidence interval -0.39--0.55); p = 5 × 10−38.

How common The A allele had a frequency of about 12% in the people studied.

Where it sits Chromosome 1, band 1q25.3 — in an intron of LAMC2.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Laminin subunit gamma-2 levels (LAMC2.9580.5.3) compared to the general population.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Laminin subunit gamma-2 levels (LAMC2.9580.5.3).
G/G Published research associates this genotype with typical/baseline likelihood of Laminin subunit gamma-2 levels (LAMC2.9580.5.3) — no copies of the reported risk allele.
Source

Questions about rs3768610

What is rs3768610?

rs3768610 is a single position in the genome, in or near the LAMC2 gene. Published research associates it with laminin subunit gamma-2 levels (lamc2.9580.5.3). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs3768610 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs3768610 come from?

GWAS Catalog, Nature 2018, PMID:29875488. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Laminin subunit gamma-2 levels (LAMC2.9580.5.3) (rs3768610). MyGeneLog™. https://www.mygenelog.com/variants/rs3768610

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