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Red blood cell count

PROX1 · rs3767844

Where this position leads

Condition: Blood Cell Counts

rs3767844 Condition: Blood Cell Counts Blood Cell Counts Condition rs3767844 rs3767844 PROX1

What the study found

Who was studied 172,952 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0328 higher (95% confidence interval 0.025-0.041); p = 1 × 10−16.

How common The G allele had a frequency of about 29% in the people studied.

Where it sits Chromosome 1, band 1q32.3 — in an intron of PROX1.

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Red blood cell count — no copies of the reported risk allele.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Red blood cell count.
G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Red blood cell count compared to the general population.
Source

Questions about rs3767844

What is rs3767844?

rs3767844 is a single position in the genome, in or near the PROX1 gene. Published research associates it with red blood cell count. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs3767844 linked to?

On MyGeneLog this position is linked to Blood Cell Counts. The research behind each link, and its sources, are set out on that condition page.

Does having rs3767844 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs3767844 come from?

GWAS Catalog, Cell 2016, PMID:27863252. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Red blood cell count (rs3767844). MyGeneLog™. https://www.mygenelog.com/variants/rs3767844

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