ABCA7 · rs3764650
Where this position leads
Condition: Dementia with Lewy Bodies
What the study found
Who was studied 44,009 European ancestry cases, 466,606 European ancestry controls.
The effect Each copy of the G allele shifted the measure 0.114 higher (95% confidence interval 0.075-0.153); p = 1 × 10−8.
How common The G allele had a frequency of about 10% in the people studied.
Where it sits Chromosome 19, band 19p13.3 — in an intron of ABCA7.
rs3764650 is a single position in the genome, in or near the ABCA7 gene. Published research associates it with dementia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
On MyGeneLog this position is linked to Dementia with Lewy Bodies. The research behind each link, and its sources, are set out on that condition page.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Alzheimer's & dementia : the journal of the Alzheimer's Association 2024, PMID:39046104. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Dementia (rs3764650). MyGeneLog™. https://www.mygenelog.com/variants/rs3764650