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MSLN protein levels

near MSLN · rs3764246

What the study found

Who was studied 488 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.74 higher (95% confidence interval 0.64-0.84); p = 8 × 10−42.

Where it sits Chromosome 16, band 16p13.3 — between genes, 0.6 kb from MSLN.

What each result means

A/A No copy of the version the research linked to MSLN protein levels. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to MSLN protein levels. That is a smaller link than two copies.
G/G Two copies of the version the research linked to MSLN protein levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs3764246

What is rs3764246?

rs3764246 is a single position in the genome, in or near the near MSLN gene. Published research associates it with msln protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs3764246 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs3764246 come from?

GWAS Catalog, Scientific reports 2024, PMID:38565889. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

MSLN protein levels (rs3764246). MyGeneLog™. https://www.mygenelog.com/variants/rs3764246

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