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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 437,194 European ancestry individuals; replicated in 315,572 European ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.00598 higher (95% confidence interval 0.0049-0.007); p = 3 × 10−29.
How common The T allele had a frequency of about 67% in the people studied.
Where it sits Chromosome 2, band 2q21.2 — in an intron of GPR39.
What each result means
C/CNo copy of the version the research linked to Liver enzyme levels (gamma-glutamyl transferase). This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Liver enzyme levels (gamma-glutamyl transferase). That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Liver enzyme levels (gamma-glutamyl transferase). That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2021 · PMID 33972514 · open access
Questions about rs3762465
What is rs3762465?
rs3762465 is a single position in the genome, in or near the MIR9986 gene. Published research associates it with liver enzyme levels (gamma-glutamyl transferase). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs3762465 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs3762465 come from?
GWAS Catalog, Nature communications 2021, PMID:33972514. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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