Sensitive

Kidney stone disease

near PTGER1 · rs3760702

Where this position leads

Condition: Urolithiasis

rs3760702 Condition: Urolithiasis Urolithiasis Condition rs3760702 rs3760702 near PTGER1

What the study found

Who was studied 13,746 East Asian ancestry cases, 241,425 East Asian ancestry controls, 17,969 European ancestry cases, 702,230 European ancestry controls.

The effect Each copy of the A allele carried 1.09 times the odds of Kidney stone disease (95% confidence interval 1.07-1.11); p = 3 × 10−19.

How common The A allele had a frequency of about 28% in the people studied.

Where it sits Chromosome 19, band 19p13.12 — between genes, 0.2 kb from PTGER1.

What each result means

A/A Two copies of the version the research linked to Kidney stone disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Kidney stone disease. That is a smaller link than two copies.
G/G No copy of the version the research linked to Kidney stone disease. This is the starting point the study compared everyone against.
Source

Questions about rs3760702

What is rs3760702?

rs3760702 is a single position in the genome, in or near the near PTGER1 gene. Published research associates it with kidney stone disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs3760702 linked to?

On MyGeneLog this position is linked to Urolithiasis. The research behind each link, and its sources, are set out on that condition page.

Does having rs3760702 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs3760702 come from?

GWAS Catalog, Nature communications 2025, PMID:40216741. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Kidney stone disease (rs3760702). MyGeneLog™. https://www.mygenelog.com/variants/rs3760702

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