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Who was studied 283,749 European ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.369 higher (95% confidence interval 0.25-0.48); p = 3 × 10−10.
Where it sits Chromosome 15, band 15q23 — at a splice region of NR2E3.
What each result means
A/ATwo copies of the version the research linked to Height (standard GWA). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Height (standard GWA). That is a smaller link than two copies.
G/GNo copy of the version the research linked to Height (standard GWA). This is the starting point the study compared everyone against.
Nature human behaviour · 2023 · PMID 37106081 · open access
Questions about rs3759815
What is rs3759815?
rs3759815 is a single position in the genome, in or near the NR2E3 gene. Published research associates it with height (standard gwa). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs3759815 linked to?
On MyGeneLog this position is linked to Height. The research behind each link, and its sources, are set out on that condition page.
Does having rs3759815 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs3759815 come from?
GWAS Catalog, Nature human behaviour 2023, PMID:37106081. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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