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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 417 European ancestry cases, 5,199 European ancestry controls.
The effect
The reported allele is C; the catalogue records no effect size
; p = 7 × 10−11.
How common The C allele had a frequency of about 5% in the people studied.
Where it sits Chromosome 14, band 14q32.11 — in a regulatory region of TDP1.
What each result means
C/CTwo copies of the version the research linked to Uveal melanoma with any chromosomal aberration. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/GOne copy of the version the research linked to Uveal melanoma with any chromosomal aberration. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Uveal melanoma with any chromosomal aberration. This is the starting point the study compared everyone against.
rs3759710 is a single position in the genome, in or near the TDP1 gene. Published research associates it with uveal melanoma with any chromosomal aberration. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs3759710 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs3759710 come from?
GWAS Catalog, Melanoma research 2020, PMID:31626034. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Uveal melanoma with any chromosomal aberration (rs3759710). MyGeneLog™. https://www.mygenelog.com/variants/rs3759710