Sensitive

Inflammatory or infectious upper respiratory disease

NEK6 · rs3758213

What the study found

Who was studied 61,197 Finnish ancestry cases, 199,208 Finnish ancestry controls.

The effect Each copy of the T allele carried 0.95 times the odds of Inflammatory or infectious upper respiratory disease (95% confidence interval 0.93-0.97); p = 2 × 10−10.

How common The T allele had a frequency of about 38% in the people studied.

Where it sits Chromosome 9, band 9q33.3 — in an intron of NEK6.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Inflammatory or infectious upper respiratory disease — no copies of the reported risk allele.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Inflammatory or infectious upper respiratory disease.
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Inflammatory or infectious upper respiratory disease compared to the general population.
Source

Questions about rs3758213

What is rs3758213?

rs3758213 is a single position in the genome, in or near the NEK6 gene. Published research associates it with inflammatory or infectious upper respiratory disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs3758213 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs3758213 come from?

GWAS Catalog, Nature communications 2023, PMID:36653354. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Inflammatory or infectious upper respiratory disease (rs3758213). MyGeneLog™. https://www.mygenelog.com/variants/rs3758213

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