Sensitive

Serum metabolite concentrations in chronic kidney disease

NAT8 · rs375811360

Where this position leads

Condition: Serum Metabolites in Chronic Kidney Disease

rs375811360 Condition: Serum Metabolites in Chronic Kidney Disease Serum Metabolites in Chronic Kidney… Condition rs375811360 rs375811360 NAT8

What the study found

Who was studied 1,143 European ancestry cases.

The effect Each copy of the G allele shifted the measure 0.84 lower (95% confidence interval 0.75-0.93); p = 1 × 10−62.

Where it sits Chromosome 2, band 2p13.1 — in an intron of ALMS1P1.

What each result means

C/C No copy of the version the research linked to Serum metabolite concentrations in chronic kidney disease. This is the starting point the study compared everyone against.
C/G One copy of the version the research linked to Serum metabolite concentrations in chronic kidney disease. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Serum metabolite concentrations in chronic kidney disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs375811360

What is rs375811360?

rs375811360 is a single position in the genome, in or near the NAT8 gene. Published research associates it with serum metabolite concentrations in chronic kidney disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs375811360 linked to?

On MyGeneLog this position is linked to Serum Metabolites in Chronic Kidney Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs375811360 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs375811360 come from?

GWAS Catalog, J Am Soc Nephrol 2018, PMID:29545352. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Serum metabolite concentrations in chronic kidney disease (rs375811360). MyGeneLog™. https://www.mygenelog.com/variants/rs375811360

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