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Triglycerides to total lipids ratio in small HDL

near INTS10 · rs3758060

What the study found

Who was studied 115,082 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.201 lower (95% confidence interval 0.16-0.24); p = 3 × 10−20.

How common The T allele had a frequency of about 99% in the people studied.

Where it sits Chromosome 8, band 8p21.3 — between genes, 0.9 kb from INTS10.

What each result means

C/C No copy of the version the research linked to Triglycerides to total lipids ratio in small HDL. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Triglycerides to total lipids ratio in small HDL. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Triglycerides to total lipids ratio in small HDL. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs3758060

What is rs3758060?

rs3758060 is a single position in the genome, in or near the near INTS10 gene. Published research associates it with triglycerides to total lipids ratio in small hdl. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs3758060 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs3758060 come from?

GWAS Catalog, PLoS biology 2022, PMID:35213538. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Triglycerides to total lipids ratio in small HDL (rs3758060). MyGeneLog™. https://www.mygenelog.com/variants/rs3758060

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