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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 2,006 Erasmus Rucphen Family (founder/genetic isolate) individuals, 26,692 European ancestry individuals.
The effect
Each copy of the A allele shifted the measure 8.96 lower (95% confidence interval 6.26-11.65); p = 7 × 10−11.
How common The A allele had a frequency of about 19% in the people studied.
Where it sits Chromosome 7, band 7q22.1 — in an intron of SRRT.
What each result means
A/ATwo copies of the version the research linked to RR interval (heart rate). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to RR interval (heart rate). That is a smaller link than two copies.
G/GNo copy of the version the research linked to RR interval (heart rate). This is the starting point the study compared everyone against.
European journal of human genetics : EJHG · 2019 · PMID 30679814 · open access
Questions about rs3757868
What is rs3757868?
rs3757868 is a single position in the genome, in or near the SRRT gene. Published research associates it with rr interval (heart rate). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs3757868 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs3757868 come from?
GWAS Catalog, Eur J Hum Genet 2019, PMID:30679814. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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